Combination therapy with beta-adrenoceptor blockers and calcium antagonists.
نویسندگان
چکیده
منابع مشابه
Alpha- and beta-adrenoceptor antagonists.
Antagonists acting on the betaor alphaadrenoceptors are used widely in medicine and in anaesthesia. The major indications for betaadrenoceptor blockade are coronary artery disease and arterial hypertension, while those for alphaadrenoceptor blockade include arterial hypertension, paroxysmal hypertension and chronic cardiac failure. The adrenoceptor antagonists interfere with important regulator...
متن کاملPharmacokinetics of beta-adrenoceptor blockers in obese and normal volunteers.
AIMS Obesity can modify the pharmacokinetics of lipophilic drugs. As beta-adrenoceptor blockers (BB) are often prescribed for obese patients suffering from hypertension or coronary heart disease, this study compares the pharmacokinetics of lipophilic beta-adrenoceptor blockers in obese and control subjects. METHODS Nine obese (157 +/- 24% of ideal body weight (IBW) mean +/- s.d.) and nine non...
متن کاملAn evaluation of beta-blockers, calcium antagonists, nitrates, and alternative therapies for stable angina.
Searching MEDLINE (from 1966 to 1997) and EMBASE (from 1974 to 1997) were searched for publications in the English language using the following search criteria: MeSH term 'angina pectoris' or the textword 'angina', and publication type 'randomized controlled trial' or textword containing a form of the word 'random'. The authors also performed searches using publication type 'controlled clinical...
متن کاملMeta-analysis of trials comparing beta-blockers, calcium antagonists, and nitrates for stable angina.
CONTEXT Which drug is most effective as a first-line treatment for stable angina is not known. OBJECTIVE To compare the relative efficacy and tolerability of treatment with beta-blockers, calcium antagonists, and long-acting nitrates for patients who have stable angina. DATA SOURCES We identified English-language studies published between 1966 and 1997 by searching the MEDLINE and EMBASE da...
متن کاملBeta-adrenoceptor blockers in chronic heart failure--a review.
There are now considerable clinical trial data to support the use of beta-adrenoceptor blockers in patients with chronic heart failure due to systolic left ventricular dysfunction. Increases in ejection fraction, improved well-being as judged by both patient and physician and reduced progression of ventricular dysfunction have been demonstrated. From meta-analyses of available trial data, a mor...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1986
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1986.tb02865.x